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In many experimental animal models, MTX has been found to increase serum urea and creatinine levels (Reference Moodi, Hosseini and Abedini16,Reference Tousson, Zaki and Abu-Shaeir50,Reference Jafaripour, Naserzadeh and Alizamani51) , but there are also studies showing that MTX reduces serum urea concentration (Reference Budancamanak, Kanter and Demirel52Reference Severin, Campagno and Brandoni54)

Additionally, ongoing monitoring and reporting of research outcomes are essential to contribute to the scientific understanding of these compounds

These hormones do not just regulate appetite and metabolism

According to Sekhar et al., diabetic patients exhibit erythrocyte glutathione concentrations up to 73.8% lower than those of healthy adults [1]

The ameliorative effect of berberine and coenzyme Q10 in an ovalbumin-induced allergic rhinitis model